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Article in Japanese
Abstract
Case Report
A Case of Churg-Strauss Syndrome in which Positive Rheumatoid Factor and MPO-ANCA Preceded the Development of Clinical Symptoms of Vasculitis
Masashi Furuiye Kazunori Konno Yuki Sumi Yoshio Ohtani Megumi Sawada Takeshi Umino Naohiko Inase Shuji Miyake Yasuyuki Yoshizawa
Department of Pulmonary Medicine, Tokyo Medical and Dental University
ABSTRACT
A 52-year-old man in whom bronchial asthma had been diagnosed in 1995 was admitted for the treatment of Churg-Strauss syndrome in June 1997. Positive tests MPO-ANCA and rheumatoid factor preceded the symptoms of vasculitis for several months. A skin biopsy revealed infiltration of eosinophils in the vessel walls, and the diagnosis of Churg-Strauss syndrome was confirmed. After systemic administration of corticosteroids, the symptoms other than mononeuritis improved markedly, and his MPO-ANCA and rheumatoid factor became negative. Rheumatoid factor and MPO-ANCA may be useful for the early diagnosis of Churg-Strauss syndrome in patients with bronchial asthma in which a well-controlled disease develops into an intractable condition.
KEYWORDS
Churg-Strauss syndrome Rheumatoid factor MPO-ANCA Vasculitis
Received 平成12年8月23日
JJRS, 39(6): 410-414, 2001
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