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Abstract

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Article in Japanese

Case Report

A case of allergic granulomatosis and angiitis without symptoms of asthma

Yoshitaka Morimatsu1)  Masaharu Kinoshita1)  Takeharu Koga1)  Hisamichi Aizawa1) 

1)First Department of Internal Medicine Kurume University School of Medicine 67, Asahi-machi, Kurume-city, Fukuoka, Japan

ABSTRACT

We present a case of allergic rhinitis in a 68-year-old woman in whom eosinophilia was found when she complained of common cold-like symptoms. The patient noticed a mass lesion on her left neck, which improved with antibiotic treatment, but her coughing continued and edema of both lower extremities appeared. She was admitted to our hospital, because of abnormalities in her electrocardiogram and cardiomegaly seen in a chest radiograph. The discomfort due to the edema in the soles of both feet remained even after steroid therapy. Her chest radiograph revealed ground-glass opacity, and a transbronchial lung biopsy revealed granulation tissue with the infiltration of eosinophils into the interstitium. Allergic granulomatosis angiitis was diagnosed because of granulomatosis vasculitis resulting from sural nerve biopsy. This was a rare case of allergic granulomatosis angiitis because her lung function was normal, she had no history of bronchial asthma, and there were no clear symptoms of bronchial asthma.

KEYWORDS

Allergic granulomatosis and angiitis  Anti-neutrophil cytoplasmic antibody  Bronchial asthma  Allergic rhinitis  Multiple mononeuritis 

Received 平成15年1月6日

JJRS, 41(9): 655-659, 2003

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