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Article in Japanese
A case of pulmonary MALT lymphoma with 6-year natural history
Miki Satoh1) Osamu Wakabayashi1) Eisei Jinushi1) Fumiaki Yoshida1) Nozomu Iwashiro2) Yoshikazu Araya1)
1)Department of Respiratory Medicine, National Hospital Organization, Hakodate Hospital 2)Department of Chest Surgery, National Hospital Organization, Hakodate Hospital
A 58-year-old asymptomatic man was referred for investigation of an abnormal shadow on chest X-ray films. Chest computed tomography (CT) revealed an infiltrative shadow containing an air-bronchogram. Video-assisted thoracic surgery was performed for a lung biopsy of an abnormal region in the right upper lobe of the lung. Based on immunohistochemical examinations and gene analysis, the abnormal shadow was diagnosed as primary pulmonary B-cell lymphoma of mucosa-associated lymphoid tissue, t(11; 18)/API2-MALT1. Rituximab-CHOP therapy yieled a complete response. He had abnormal shadows on chest X-ray films in both lung fields since 6 years previously. Retrospective examination of chest radiographs revealed slow growth during the 6 years.
Pulmonary MALT lymphoma Medical checkup Chest radiograph Natural course Pathologic findings
Received 平成20年5月7日
JJRS, 46(12): 1013-1018, 2008