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Article in Japanese
Abstract
Case Report
A Good syndrome associated with pure red cell aplasia
Tadahisa Numakura Yoshifumi Matsuura Hiroto Takiguchi Yasuka Hara Kouken Ameku
Ohta General Hospital Fundation, Ohta Nishinouchi Hospital, Center of Respiratory Disorders
ABSTRACT
A 78-year-old woman was admitted because of persistent cough, fever and sputum for one week. She had been treated with radiation therapy for inoperable thymoma complicated by severe heart failure and had been suffering from recurrent pneumonia and otitis media since then. A chest radiograph on admission showed an anterior mediastinal mass shadow and infiltrates in the bilateral lower lung fields. Serum gamma globulin was decreased and erythroid cells in the bone marrow were markedly decreased. Thymoma with hypo-gammaglobulinemia is called Good syndrome. We reported this very rare case of Good syndrome. After improving the infection, cyclosporine A was administered for PRCA and hypo-gamma globulinemia, but we discontinued this due to liver dysfunction. We have been currently continuing her treatment with red blood cell transfusion and immunoglobulin supplement only.
KEYWORDS
Good syndrome Pure red cell aplasia Thymoma Hypo-gammaglobulinemia
Received 平成22年11月9日
JJRS, 49(9): 647-650, 2011
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