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Article in Japanese
Efficacy of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of chest and mediastinal diseases
Daisuke Minamia Nagio Takigawab Katsuyuki Hottaa Toshi Murakamia Eiki Ichiharaa Hisaaki Tanakaa Akiko Hisamotoa Yasushi Tanimotoa Mitsune Tanimotoa Katsuyuki Kiuraa
a Department of Respiratory Medicine, Okayama University Hospital
b Department of General Internal Medicine 4, Kawasaki Medical School
From May 2009 to December 2010, forty patients underwent endobronchial ultrasound transbronchial needle aspirations (EBUS-TBNA) in our hospital. We examined their medical records to obtain information concerning the diagnosis yields, the sites and sizes of lymph nodes, the number of needle passes, and other complications. The definitive diagnoses were made using EBUS-TBNA in 26 patients (9 lung adenocarcinomas, 4 lung squamous cell carcinomas, 4 small-cell carcinomas, 3 nonsmall cell lung carcinomas, 1 mesothelioma, 1 lymphoma, 3 sarcoidoses, and 1 tuberculosis lymphadenopathy; sensitivity, 74.2%; specificity, 100%). Active epidermal growth factor receptor gene mutation was found in 2 adenocarcinomas using EBUS-TBNA specimens. The median of the longest diameter in 44 lymph nodes from 40 patients was 22 mm (range 10-60), and the median number of needle passes was 2 times (range 1-5). Five patients experienced fever and bloody sputum; however, no severe complications appeared. EBUS-TBNA seemed useful for diagnosing not only mediastinal and hilar lymph-node metastases in patients with lung cancer, but also mesotheliomas, lymphomas, sarcoidoses, and mycobacterium infections.
Endobronchial ultrasound-guided transbronchial needle aspiration Epidermal growth factor receptor gene mutation Malignant mesothelioma Malignant lymphoma Tuberculosis lymphadenopathy
Received 30 Jun 2011 / Accepted 18 Oct 2011
AJRS, 1(2): 102-106, 2012