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Article in Japanese
Abstract
Case Report
Intractable bladder hemorrhage caused by bladder metastasis in a patient with advanced pulmonary adenocarcinoma
Akihiko Goto Takeo Ito Taiki Masuda Yutaka Mukai Mari Yamasue Jun-ichi Kadota
Department of Respiratory Medicine and Infectious Diseases, Oita University Faculty of Medicine
ABSTRACT
A 58-year-old man was diagnosed as pulmonary adenocarcinoma (cT4N3M0, stage IIIb). Although he underwent first-line chemotherapy, multiple metastases were found thereafter. Only a bladder metastasis enlarged after second-line chemotherapy, and he was hospitalized for control of continuous bladder hemorrhaging. Although the bladder hemorrhaging was intractable, it was controlled by transcatheter arterial embolization. He underwent partial cystectomy afterward, and the resected bladder specimens demonstrated metastases from the pulmonary adenocarcinoma. A bladder metastasis from pulmonary adenocarcinoma is very rare. As a cause of only a bladder metastasis enlargement, we considered a possibility of the pharmacokinetic drug concentration difference of each organ or the tumor cell heterogeneity about drug resistance.
KEYWORDS
Pulmonary adenocarcinoma Bladder matastasis Bladder hemorrhage Transcatheter arterial embolization
Received 19 Jul 2013 ／ Accepted 20 Jan 2014
AJRS, 3(3): 401-404, 2014
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