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Article in Japanese
A case of allergic bronchopulmonary mycosis caused by Curvularia species
Mayumi Nishimotoa Mitsuhiro Yamaguchia Akari Kouzenb Hirotsugu Fujiib Akihito Uedaa Katsuhiko Kameic
aDepartment of Internal Medicine, Minoh City Hospital
bDepartment of Microbiology Laboratory, Minoh City Hospital
cMedical Mycology Research Center, Chiba University
The patient was a 38-year-old woman who had experienced a sore throat of eight months duration. Although the soreness had soon disappeared, a dry cough appeared, which made her to visit our hospital. Chest X-ray examination revealed some nodular opacities and a consolidation in the left middle lung. Chest computed tomography (CT) revealed the bronchiectasis filled with mucoid impactions in the left lingular segment. Bronchoscopy demonstrated a narrowing in the entrance of left B5 as a result of mucoid impaction. The levels of total-serum IgE and Aspergillus-specific IgE were high; therefore our tentative diagnosis was allergic bronchopulmonary aspergillosis. Curvularia lunata was then isolated from her bronchial lavage fluid. Moreover, neither antigen nor antibody of Aspergillus was positive. Thus our final diagnosis was allergic bronchopulmonary mycosis caused by C. lunata. We started the treatment with prednisolone (25 mg/day), but it did not work well. Consequently, we added voriconazole (300 mg/day). With these therapies, her symptoms and radiological findings improved.
Curvularia lunata Allergic bronchopulmonary mycosis Allergic bronchopulmonary aspergillosis Voriconazole
Received 8 Oct 2013 / Accepted 3 Mar 2014
AJRS, 3(4): 553-557, 2014