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Article in Japanese
A case of eosinophilic pleural effusion associated with allergic bronchopulmonary aspergillosis
Keiko Tanimura Wataru Furutani Kouji Date Yutaka Kubota
Department of Respiratory Medicine, Kyoto Second Red Cross Hospital
Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity reaction to colonized Aspergillus species, that typically occurred in asthmatic patients. A 79-year-old man was admitted with low-grade fever and infiltrate and bronchiectasis of the left lung. He had no asthmatic symptoms, but showed eosinophilic pleural effusion. He was diagnosed with ABPA due to the following Rosenberg's criteria: peripheral blood eosinophilia, a high serum IgE level, positive precipitating serum antibodies to Aspergillus, immediate skin reaction to Aspergillus antigens, pulmonary infiltrate, and central bronchiectasis. This case was successively controlled by the addition of an antifungal agent to corticosteroids used as monotherapy, the eosinophilic pleural effusion was also improved. This is the third reported case of ABPA with eosinophilic pleural effusion. We discuss the association between ABPA and pleural effusion, and the efficacy of the combination of corticosteroids and antifungal therapy for ABPA.
Allergic bronchopulmonary aspergillosis (ABPA) Pleural effusion Eosinophilia
Received 23 Oct 2014 / Accepted 13 Jan 2015
AJRS, 4(3): 249-252, 2015