Two cases of lung adenocarcinoma with Trousseau syndrome successfully treated with chemotherapy
Junichi Fujita Kenya Kuramoto Takafumi Shimada Keiji Fujiwara Fumi Mochizuki Hiroichi Ishikawa
Department of Respiratory Medicine, Tsukuba Medical Center Hospital
Trousseau syndrome, which is often associated with advanced cancer, reportedly has a poor prognosis. We describe two cases with hypercoagulability resulting from Trousseau syndrome, which was ameliorated by treatment for lung adenocarcinoma. Case 1 was a 69-year-old man. In association with lung adenocarcinoma recurrence, he developed concomitant thrombosis and was diagnosed as having Trousseau syndrome. He was EGFR-gene mutation positive and started to receive gefitinib, which ameliorated the hypercoagulability. Case 2 was a 52-year-old woman. She developed thrombosis and was diagnosed as having lung adenocarcinoma associated with concurrent Trousseau syndrome. Hypercoagulability was ameliorated by combination chemotherapy with carboplatin and pemetrexed.
Lung cancer Trousseau syndrome
Received 15 Jun 2016 / Accepted 21 Sep 2016
AJRS, 6(1): 13-17, 2017