A case of synovial sarcoma in the thoracic cavity
Mami Orimoa Tomohito Nagaib Sayo Fujimotoa Takako Matsumotoc Kazuyuki Nisimurab Jun Tamaokia
aFirst Department of Medicine, Tokyo Women's Medical University
bDepartment of Respiratory Medicine, Saiseikai Kurihashi Hospital
cDepartment of Thoracic Surgery, Tokyo Women's Medical University
A 72-year-old man admitted to our hospital with exertional dyspnea. The chest X-ray revealed right pleural effusion, and chest computed tomography showed multiple large tumors from the diaphragm side with pleural effusion. A pleural effusion examination revealed lymphocytic exudate and showed no atypical cells. A thoracoscopy was performed, and several protruded tumors showed from the diaphragm side. A histopathological examination revealed a spindle cell tumor. Immunohistochemically, the spindle cells were negative for EMA, AE1/AE3, S-100, desmin, calretinin, α-SMA, stat6, CD34. The SYT-SSX fusion gene was detected via fluorescence in situ hybridization, and a synovial sarcoma was diagnosed in the thoracic cavity. Synovial sarcoma occurs most commonly as primary neoplasm of the extremities. We report a rare case of synovial sarcoma in the thoracic cavity.
Synovial sarcoma Thoracoscopy Pleural effusion Pleura SYT gene
Received 24 Mar 2017 / Accepted 28 Jun 2017
AJRS, 6(5): 341-345, 2017