We adapted an existing pressure-sensor sheet for screening sleep apnea–hypopnea syndrome (Sleep EYE^®, Denso Co. Ltd.) to develop an in-home monitoring system for patients with chronic lung disease (CLD) to monitor in-bed and bed-leaving, respiratory rate (RR), breathing pattern, body movement (BM), SpO₂, and pulse rate, and examined its effectiveness in 6 healthy volunteers and 8 elderly patients with CLD. When compared with the volunteers, the CLD patients experienced higher RR, increased apnea–hypopnea and hypoventilation, more cumulative time with SpO₂<90%, and increased BM at night. The measurements taken at home every day for 1 week showed that the CLD patients experienced significantly increased in-bed time, frequency of getting out of bed at night, and in-bed time during the daytime when compared with the volunteers. These findings suggest that the newly developed pressure sensor sheet system may be useful as an in-home monitoring system for elderly CLD patients.