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Article in Japanese
A case of paragonimiasis mimicking lung cancer diagnosed by immunological tests
Hidetaka Majimaa,b Tetsu Haraa Reina Imasec Yasuto Jina Osamu Matsubarad Yasunari Miyazakib
aDepartment of Respiratory Medicine, Hiratsuka Kyosai Hospital
bDepartment of Respiratory Medicine, Tokyo Medical and Dental University
cDepartment of Respiratory Medicine, Yokohama City Minato Red Cross Hospital
dDepartment of Pathology, Hiratsuka Kyosai Hospital
A 60-year-old Laotian man who had presented with cough and chest pain was referred to our hospital. A chest computed tomography (CT) scan showed a mass shadow on the left upper lobe, and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) CT revealed increased FDG uptake in the lesion. Although lung cancer was strongly suggested, transbronchial biopsy of the mass showed only eosinophilic infiltration. Detailed history taking revealed that he had eaten raw crabs. Although no Paragonimus ova or worms were detected by bronchoscopy, immunological tests showed that his serum contained specific antibodies against paragonimiasis antigens, and he was therefore diagnosed with paragonimiasis by serology. A shadow with histopathologically detected eosinophilic infiltration is suggestive of paragonimiasis, although it is difficult to differentiate it from lung cancer when there is increased FDG uptake in the lesion. It is important to take a detailed history including travels and meals. Immunological tests are useful for diagnosing paragonimiasis.
Paragonimiasis Immunodiagnosis
Received 4 Jul 2019 / Accepted 31 Oct 2019
AJRS, 9(1): 38-42, 2020