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Article in Japanese
A case of lung Langerhans-cell histiocytosis that relapsed on administration of NEO CEDAR
Syunichi Kohnoa Kazunobu Tachibanaa,b Takatoshi Enomotoa Yuichi Adachia Koji Azumaa Yoshikazu Inoueb
aDepartment of Internal Medicine, National Hospital Organization Kinki-Chuo Respiratory Medical Center
bClinical Research Center, National Hospital Organization Kinki-Chuo Respiratory Medical Center
A 51-year-old woman visited a local doctor with fatigue. Chest X-ray showed multiple nodules in the bilateral lung fields, and she was referred to our hospital. She was diagnosed with pulmonary Langerhans-cell histiocytosis (PLCH) by lung biopsy and whole-body examination. Although smoking cessation alleviated the multiple nodular shadows, the inhalation of NEO CEDAR caused further multiple nodular shadows. NEO CEDAR, which is sold over the counter at pharmacies as a cough suppressant, also comes in cigarette form. When the patient was instructed to discontinue NEO CEDAR inhalation, the multiple nodules in the lung field disappeared again. There have been no reports of NEO CEDAR aggravating smoking-related conditions. It has been reported that in cigarette form it contains some of the same components as cigarettes, and it is speculated that these common components are involved in the progression of PLCH.
Langerhans-cell histiocytosis (LCH) Smoking NEO CEDAR
Received 1 Aug 2019 / Accepted 1 Oct 2019
AJRS, 9(1): 43-47, 2020