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Article in Japanese
Abstract
Case Report
A case of cardiac angiosarcoma diagnosed by cardiac biopsy using intracardiac echocardiography that reacted well to paclitaxel
Komei Yanasea Chizuru Sakaia Yasushi Ohnoa Ayumi Niwab Norihiko Funaguchic Hiroyuki Okuraa
aDepartment of Cardiology and Respiratory Medicine, Gifu University, Tokai National Higher Education and Research System
bDepartment of Tumor Pathology, Gifu University Graduate School of Medicine, Tokai National Higher Education and Research System
cDepartment of Respiratory Medicine, Asahi University Hospital
ABSTRACT
A 45-year-old woman complained of cough, bloody sputum, and exertional dyspnea. Contrast-enhanced computed tomography showed patchy pulmonary infiltrates and a right atrial mass. She underwent cardiac catheterization and was diagnosed with angiosarcoma by cardiac biopsy of the tumor using intracardiac echocardiography. The clinical diagnosis of the lung lesions was multiple lung metastases. Treatment with first-line paclitaxel and second-line pazopanib for angiosarcoma was performed. Paclitaxel was especially effective, and a partial response was confirmed 10 months after chemotherapy. However, pazopanib was difficult to continue due to prolonged thrombocytopenia as an adverse event. She survived about 14 months from diagnosis, it was comparable to the median overall survival for unresectable cardiac angiosarcoma.
KEYWORDS
Cardiac angiosarcoma Paclitaxel Pazopanib Cardiac tumor biopsy using intracardiac echocardiography
Received 2 Sep 2020 ／ Accepted 16 Dec 2020
AJRS, 10(2): 127-133, 2021
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