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Article in Japanese
Abstract
Case Report
A case of IgG4-related disease with pleuritis after receiving the COVID-19 vaccination
Yoshiki Yataa Yuji Itoa Takashi Akiyamab Masayuki Yamajib Hiroki Numanamib Toshio Katoc
aDepartment of Respiratory Medicine, Daiyukai General Hospital
bDepartment of Respiratory Surgery, Daiyukai General Hospital
cDepartment of Pathology, Daiyukai General Hospital
ABSTRACT
A 79-year-old man developed a cough and a right-sided pleural effusion after receiving the fourth COVID-19 vaccination; therefore, thoracentesis was performed. The pleural effusion was exudative and had a high adenosine deaminase (ADA) level. A diagnosis could not be reached, and a pleural biopsy was performed. Histopathology showed IgG4-positive plasma cells and lymphocytic infiltration, and a diagnosis of pleurisy caused by an IgG4-related disease was made. After starting steroid treatment, the pleural effusion and subjective symptoms improved. In addition to tuberculous pleurisy, we believe that pleurisy caused by IgG4-related diseases should be considered in cases of pleural effusion with high ADA levels.
KEYWORDS
IgG4-related disease Pleural effusion Adenosine deaminase (ADA) Coronavirus disease 2019 (COVID-19) vaccination Eosinophilia
Received 28 Nov 2023 ／ Accepted 5 Mar 2024
AJRS, 13(3): 106-110, 2024
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