We report two cases of Löfgren's syndrome that occurred in males. Case 1: A 44-year-old man visited our hospital because of fever, cough, and arthralgia. Chest computed tomography (CT) scan showed multiple pulmonary nodules and lymphadenopathy of the hilum and mediastinum. We performed a surgical lung biopsy of the nodules and epithelioid cell granulomas were detected. We diagnosed him with Löfgren's syndrome (incomplete type). His symptoms spontaneously remitted, and the multiple nodules and lymphadenopathies had improved a month after his discharge. Case 2: A 34-year-old man presented to the clinic due to fever, arthralgia, and skin rash. His skin rash was considered as erythema nodosum, and his chest CT scan showed multiple nodules in both lung fields and lymphadenopathy of the hilum and mediastinum. He was referred to our hospital for further examination and treatment. We performed a surgical lung biopsy, and epithelioid cell granulomas were detected. We diagnosed him with Löfgren's syndrome and his symptoms healed naturally without any medication. In Japan, only a few cases of Löfgren's syndrome have been reported, especially in males. However, case reports of Löfgren's syndrome in males have increased in recent years. There are many variations of Löfgren's syndrome, and they may lack the ocular or cardiac involvement which are characteristic features of sarcoidosis. Therefore, we should carefully consider Löfgren's syndrome as a differential diagnosis even if there are few typical clinical findings.