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Abstract

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Article in Japanese

Case Report

A case of lymphomatoid granulomatosis with sarcoidosis that was difficult to diagnose

Haruka Motohashi  Mayuko Ishiwari  Yuta Kono  Yuki Yamaguchi  Reimi Mizushima  Shinji Abe 

Department of Respiratory Medicine, Tokyo Medical University

ABSTRACT

The patient was a 68-year-old man. During follow-up after chemoradiotherapy for prostate cancer, an enlarged intra-abdominal lymph node was noted. He underwent an upper gastrointestinal endoscopy and was suspected of having low-grade B-cell lymphoma, but a definitive diagnosis was not made. Bilateral pulmonary nodules appeared, and the patient was referred to the Department of Respiratory Medicine.
An inguinal lymph node biopsy with accumulation on FDG-PET showed no evidence of malignancy, but an epithelioid granuloma was detected. The patient underwent video-assisted thoracic surgery for a rapidly enlarging pulmonary lesion, leading to a diagnosis of lymphomatoid granulomatosis. Lymphoma may develop during the course of sarcoidosis, and prioritizing lesions considered to be highly active may aid in early diagnosis

KEYWORDS

Lymphomatoid granulomatosis  Sarcoidosis-lymphoma syndrome 

Received 6 Aug 2024 / Accepted 7 Aug 2024

AJRS, 13(6): 296-300, 2024

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