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Article in Japanese
Abstract
Case Report
A case of disseminated nocardiosis caused by Nocardia pseudobrasiliensis
Shohei Gajaa,b Morikazu Akaminea Seishiro Arimaa,b Yui Nahaa Teruhito Uchiharaa Kazuko Yamamotob
aDepartment of Respiratory Pulmonology, Okinawa Red Cross Hospital
bFirst Department of Internal Medicine, University of the Ryukyus
ABSTRACT
Pulmonary nocardiosis is a rare opportunistic infection primarily affecting immunocompromised individuals, characterized by the potential for disseminated lesions throughout various organ systems. In the current case, Nocardia pseudobrasiliensis was isolated from a pleural fluid culture, with a concomitant brain abscess identified as a disseminated manifestation of the disease. The patient underwent a comprehensive treatment regimen comprising ciprofloxacin and additional antimicrobial agents for a duration of 12 months, resulting in the successful resolution of all identified lesions. Notably, Nocardia pseudobrasiliensis exhibits a propensity for resistance to sulfamethoxazole-trimethoprim; thus, precise bacterial identification and antimicrobial susceptibility testing are imperative for effective management of this infection.
KEYWORDS
Nocardia pseudobrasiliensis Trimethoprim and sulfonamide resistance Pulmonary nocardiosis
Received 4 Oct 2024 ／ Accepted 21 Jan 2025
AJRS, 14(3): 131-135, 2025
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