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Abstract

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Article in Japanese

Case Report

Three Adults with Mild Varicella and Bronchial Mucosal Lesions

Satoshi Konno  Yasuhiro Tsuneta  Eisei Jinushi  Hideaki Ukita  Toshiyuki Harada  Akira Aida  Yoichi Nishiura  Wataru Takahashi  Terukuni Kawai 

Department of Internal Medicine, Konan Hospital 1-6 Hiragishi, Toyohira-ku Sapporo, Hokkaido, Japan

ABSTRACT

We encauntered three adults with varicella and bronchial mucosal lesions. Respiratory symptoms were minimal in all three. Chest X-ray films showed bilateral, diffuse, small, nodular shadows. Small, elevated lesions with white plaque's were seen on the bronchial mucosa bronchoscopically.Transbronchial lung biopsy, bronchial mucosal biopsy, and bronchoalveolar lavage were also done. The lung-biopsy specimen showed infiltration of lymphocytes into the interstitial space; VZV antigen was found by immunohistochemical staining of the lesion in one case. Analysis of bronchoalveolar lavage fluid revealed abnormally low CD4/8 ratios in three cases. These findings suggest a high incidence of respiratory complications, especially bronchial lesions, despite the lack of respiratory symptoms, in adults with varicella.

KEYWORDS

Adult varicella  Varicella pneumonia  Bronchial mucosal lesion 

Received 平成9年7月9日

JJRS, 36(4): 363-368, 1998

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