A Rare Case of Lung Adenocarcinoma in Cavity Wall of Pulmonary Aspergilloma
Kohji Hashiguchi Shigefumi Maesaki Eisuke Sasaki Yumiko Tomiyama Yasuhito Higashiyama Kazunori Tomono Mikio Oka Takayoshi Tashiro Shigeru Kohno
Second Department of Internal Medicine, Nagasaki University School of Medicine Takao Takahashi, Shinji Akamine, Tadayuki Oka and Hiroyoshi Ayabe First Department of Surgery, Nagasaki University School of Medicine 1-7-1 Sakamoto, Nagasaki 852-8501
A 67-year-old man was admitted with the complaint of hemosputum. Chest X-ray films resulted in a diagnosis of pulmonary aspergilloma, and treatment with intravenous amphotericin B was initiated. However, therapy was discontinued due to renal insufficiency, an adverse effect of amphotericin B. The size of the fungus ball and cavity increased despite treatment with oral itraconazole (200 mg/day). Cavernostomy was performed and the fungus ball was removed from the upper lobe of the left lung. Computed tomographic scans disclosed thickening of the remaining wall of the cavity, with destruction of the ribs. The patient experienced worsening respiratory distress and died. Necropsy revealed adenocarcinoma of the left lung.
Aspergilloma Pulmonary adenocarcinoma Amphotericin B Cavernostomy
Received 平成10年12月24日
JJRS, 37(8): 658-661, 1999