Chronic Eosinophilic Pneumonia -A follow-up study of 12 cases-
Yoshiro Mochizuki* Yoichiro kobashi** Yasuharu Nakahara* Akira Tanaka* Tetuji Kawamura* Shin Sasaki* Rieko Kawanami*
*Department of Pulmonary Medicine, National Himeji Hospital
**Department of Pathology, Tenri Yorozu Hospital
In this study, twelve cases of CEP were followed for a mean period of 10.9 years (range 9.3∼ 12.9 years) at National Himeji Hospital. Of the five women and seven men examined, two patients possessed preexisting asthma and one developed asthma during the course of CEP disease. None of the patients exhibited any symptoms of allergic rhinitis. All had dramatic responses to corticosteroid therapy without developing extrathoracic manifestations. During the course of CEP, one patient died from acute myocardial infarction. Relapses, which occurred in six patients, responded as well to the treatment as in the original episode. One patient continued long-term oral corticosteroids (5 mg/day) and steroid inhalants (800 μ g/day) as treatment for asthma. Another was administered steroid inhalants (800 μ g/day) to treat both asthma and relapsing CEP; two additional patients received 800-600 μ g/day to prevent relapse. These data indicate that, with proper treatment, the long-term prognosis for patients with CEP is excellent.
Chronic eosinophilic pneumonia Corticosteroid therapy Long-term prognosis
Received 平成13年10月29日
JJRS, 40(11): 851-855, 2002