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Article in Japanese
Abstract
Case Report
Churg-Strauss Syndrome With Alveolar Hemorrhage
Hidekazu Matsushima1) Noboru Takayanagi1) Mikio Ubukata1) Daidou Tokunaga1) Nagato Sato1) Kazuyoshi Kurashima1) Tsutomu Yanagisawa1) Yutaka Sugita1) Eishin Hoshi2) Yoshinori Kawabata3) Minoru Kanazawa1)
Departments of 1)Respiratory Medicine, 2)Respiratory Surgery, and 3)Pathology, Saitama Cardiovascular and Respiratory Center, 1696 Itai, Kohnan, Ohsato, Saitama, Japan
ABSTRACT
A 35 year-old man was admitted to our hospital because of cough, wheezing, and paresthesia of the right upper extremity. He demonstrated marked eosinophilia, bronchial asthma, and mononeuritis multiplex. We diagnosed Churg-Strauss syndrome. Serum MPO-ANCA was elevated to 189 U/ml. Chest high-resolution computed tomography showed panlobular ground-glass attenuation in both lungs. BALF showed bloody fluid, and TBLB revealed findings consistent with eosinophilic pneumonia. Lung biopsy by VATS revealed eosinophilic pneumonia, pulmonary vasculitis, capillaritis, and hemosiderosis. The patient recovered after treatment with prednisolone and cyclophosphamide. We concluded that alveolar hemorrhage due to pulmonary capillaritis could be a complication in cases of Churg-Strauss syndrome.
KEYWORDS
Churg-Strauss syndrome Alveolar hemorrhage Pulmonary vasculitis Pulmonary capillaritis VATS biopsy
Received 平成14年5月8日
JJRS, 41(1): 25-29, 2003
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