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Abstract

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Article in Japanese

Case Report

Paraneoplastic Neurologic Syndrome and Small-Cell Lung Cancer in a Patient Positive for Anti-Hu Antigen

Yoshiko Koyama  Kouichi Miyashita  Masaki Anzai  Maiko Kadowaki  Masakuni Fujita  Shirou Mizuno  Yoshitaka Totani  Yoshiki Demura  Shingo Ameshima  Takeshi Ishizaki  Isamu Miyamori 

Department of Internal Medicine, Fukui Medical University, 23-3, Shimo-Aizuki, Matsuoka-cho, Yoshida-gun, Fukui 910-1193

ABSTRACT

We encountered a case of small-cell lung cancer with paraneoplastic neurologic syndrome in a 68-year old man. Progressive dysesthesia had developed in his hands and legs over a period of 4 months. Chest radiography and chest CT scanning on admission showed a mass in the hilum of the left lung. Anti-Hu antibody was found in his serum and the subsequent histopathological diagnosis by TBLB was small cell lung cancer. The patient underwent complete remission, in terms of tumor size, as a result of concurrent chemoradiotherapy (cisplatin, etoposid) and the dysesthesia in his legs was alleviated.

KEYWORDS

Anti-Hu antibody  Small cell lung cancer  Paraneoplastic neurologic syndrome 

Received 平成14年6月12日

JJRS, 41(1): 35-38, 2003

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