A case of malignant lymphoma arising from the posterior mediastinum, with pleural effusion
Osamu Nagashima1) Kazuhisa Takahashi1) Kouichi Sato1) Tsutomu Suzuki1) Yoshinosuke Fukuchi1) Yasushi Isobe2) Kazuo Oshimi2)
1)Department of Respiratory Medicine, and 2)Department of Hematology Medicine
Department of Respiratory Medicine, Juntendo University School of Medicine
We report a rare case of malignant lymphoma arising from the posterior mediastinum with bilateral pleural effusion. A 71-year-old man was admitted to our hospital for evaluation of a posterior mediastinal tumor and bilateral pleural effusion revealed on a chest CT scan. Because no tumor tissue could be obtained by fiberbronchoscopy, video-assisted thoracoscopic surgery was performed. The tumor sample was composed of large, atypical lymphocytes positive for CD20 on immunohistochemical analysis. A diagnosis of diffuse large B cell lymphoma was made from the typical histological features. The patient was treated with combination chemotherapy (CHOP) and rituximab and improved dramatically.
Malignant lymphoma Posterior mediastinum Pleural effusion
Received 平成16年1月29日
JJRS, 42(8): 772-776, 2004