A case of cryptogenic organizing pneumonia accompanied by large bullae
Tetsuro Inoue1) Eisaku Tanaka1) Minoru Sakuramoto1) Masayoshi Minakuchi1) Yuji Maeda1) Ko Maniwa1) Kiminobu Tanizawa1) Tomoshi Takeda1) Masaki Okamoto1) Yoichiro Kobashi2) Yoshiaki Yuba2) Satoshi Noma3) Yoshio Taguchi1)
1)Department of Respiratory Medicine 2)Department of Pathology 3)Department of Radiology, Tenri Hospital
A 66-year-old man complaining of fever was given intravenous antibiotic therapy, but he did not improve. After subsequent admission, chest X-ray film and computed tomography scans showed large bullae and consolidation in the right lung field. A transbronchial lung biopsy specimen revealed infiltration of mononuclear cells in alveolar septa and organizing lesions in alveolar ducts. We considered this case to be cryptogenic organizing pneumonia (COP) from its clinical course and pathological findings. Treatment with corticosteroid resulted in disappearance of the large bullae and consolidations. COP accompanied by large bullae is very rare. The large bullae may have been caused by check-valve mechanism.
Cryptogenic organizing pneumonia Bronchiolitis obliterans organizing pneumonia Giant bulla Cystic change Transbronchial lung biopsy
Received 平成17年8月31日
JJRS, 44(7): 517-521, 2006