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Article in Japanese
Abstract
Case Report
A case of rheumatoid lung complicated by SELAPINA®-induced pneumonia
Seiko Nakayama1)3) Hiroshi Mukae1) Yuji Ishimatsu2) Kanako Sugiyama1) Mioko Ide1) Hiroshi Ishimoto1) Keiko Hisatomi1) Hiroshi Ishii1) Koh Abe3) Yoshiyuki Ozono3) Shigeru Kohno1)
1)Second Department of Internal Medicine, Nagasaki University School of Medicine 2)Department of Medicine, Nagasaki Municipal Hospital 3)Department of General Medicine, Nagasaki University Hospital
ABSTRACT
SELAPINA® is generic product of PL granule® which is one of the most common forms of combination remedies for the common cold in Japan, and includes acetaminophen. We report a case of SELAPINA®-induced pneumonia successfully treated with glucocorticoid pulse therapy followed by orally administered prednisolone. A 68-year-old woman, who had been treated for rheumatoid arthiritis with pulmonary involvement, took SELAPINA® with an antibiotic for 6 days because of her cold symptoms. She then suffered a high fever, cough, dyspnea, vomiting and diarrhea. Chest radiograph and high-resolution computed tomography (HRCT) scan revealed diffuse interstitial shadows. SELAPINA®-induced pneumonia was diagnosed because the blastoid transformation test using her peripheral blood lymphocytes was positive on stimulation with SELAPINA®, but negative for other medicines.
KEYWORDS
Drug-induced pneumonia SELAPINA® Combination remedy for colds Rheumatoid lung Drug lymphocyte stimulation test (DLST)
Received 平成18年2月23日
JJRS, 44(11): 858-863, 2006
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