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Abstract
Case Report
A case of bird related hypersensitivity pneumonitis had a progressive course
Ayumi Kohno1) Tatsuji Enomoto1) Kazuyo Kaneko1) Hitoshi Saitoh1) Ritsuko Narato1) Makiko Yomota1) Michio Tanaka2) Tamiko Takemura3) Seiichi Nakamura1)
1)Department of Respiratory Medicine, Tokyo Metropolitan Hiroo Hospital 2)Department of Examination, Tokyo Metropolitan Hiroo Hospital 3)Department of Pathology, Japan Red Cross Medical Center
ABSTRACT
A 50-year-old woman was admitted due to productive cough continuing for 3 years. A chest computed tomography showed appearance of nonspecific interstitial pneumonia (NSIP). Thoracoscopic lung biopsy specimens showed mainly a pattern of NSIP with multinucleated cells and cholesterol clefts. She was not a bird fancier, but had indirect exposure to birds in her living environment, and had been using feather-filled duvets for a long time. We established a diagnosis of bird-related hypersensitivity pneumonitis based on antibodies in serum positive to pigeon dropping extracts. She was treated by coadministration of corticosteroids and immunosuppressants, and avoidance of bird-related antigens, but had a progressive course and died of respiratory failure.
KEYWORDS
Chronic hypersensitivity pneumonitis Bird related hypersensitivity pneumonitis Interstitial pneumonia Nonspecific interstitial pneumonia (NSIP)
Received 平成19年11月7日
JJRS, 46(7): 558-563, 2008
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