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Abstract

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Article in Japanese

Original Article

Clinical analysis of eight patients with pulmonary toxocariasis

Masahide Yoshikawa1)  Noriko Koyama2)  Shigeto Hontsu2)  Yoshifumi Yamamoto2)  Shuhei Ogawa5)  Takahito Nakamura5)  Youka Mizuno5)  Sachiko Miura3)  Kei-ichi Mikasa4)  Hiroshi Kimura2) 

1)Department of Parasitology, Nara Medical University 2)The Second Department of Internal Medicine, Nara Medical University 3)Department of Radiology, Nara Medical University 4)Center for Infectious Diseases, Nara Medical University 5)Department of Respiratory Medicine, Hoshigaoka Koseinenkin Hospital

ABSTRACT

We encountered 8 adult cases of pulmonary toxocariasis. Five were asymptomatic, 1 had transient chest pain, 1 suffered from arthralgia and migrating skin pain, and 1 had chest discomfort due to pneumothorax. Infection was associated with the consumption of raw liver with paratenic hosts in 5 patients. The cause was suspected to be contact with infected young dogs in 1 case and was undetermined in 2 cases. All 8 cases showed some abnormalities in their laboratory examination results including eosinophilia (>500 /μl) and elevated IgE (>100 IU), and all had positive results in serological examinations for the larval excretory-secretory product of Toxocara canis. In 7 patients, excluding the patient with pneumothorax, chest computed tomography demonstrated multiple small pulmonary lesions, most of which were either nodules with halos, or ground-glass opacities. One patient recovered without medication, while the other 7 were treated with albendazole (ABZ) with good responses. Although the optimal duration of ABZ therapy has not been established, 4 weeks or longer seemed necessary to obtain a complete cure in pulmonary toxocariasis.

KEYWORDS

Toxocara canis  Toxocara cati  Food-borne parasitosis  Serological diagnosis  Albendazole 

Received 平成21年8月6日

JJRS, 48(5): 351-356, 2010

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