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Article in Japanese
Abstract
Case Report
A case of extraskeletal osteosarcoma in the mediastinum
Takayuki Kamanakaa Takashige Miyaharab Junichi Hottab Toshiro Suzukic Tomonobu Koizumic Takeshi Ueharad
aDepartment of General Medicine, Nagano Matsushiro General Hospital
bDepartment of Respiratory Medicine, Nagano Matsushiro General Hospital
c Department of Respiratory and Infectious Medicine, Shinshu University School of Medicine
dDepartment of Laboratory Medicine, Shinshu University School of Medicine
ABSTRACT
An 83-year-old man presented with a mass accompanied by calcification that was found on chest computed tomography during a postoperative check. A diagnosis by a transbronchial aspiration biopsy using convex bronchoscopy was malignant fibrous histiocytoma. The histological findings demonstrated spindle-shaped tumor cells with nuclear pleomorphism that were negative for immunostain of cytokeratin, smooth muscle actin, and S-100, except KP-1. He received only radiotherapy (45 Gy/15 Fr) because of his poor performance states. However, the tumor developed mesenteric metastasis rapidly with ascites. He died on the 26th day of his second admission to our hospital, and an autopsy was carried out. The final pathological diagnosis was primary extraskeletal osteosarcoma in the middle mediastinum. For a correct diagnosis, sharing clinical information with pathologists is important.
KEYWORDS
Mediastinum tumor Extraskeletal osteosarcoma Calcification Radiation therapy Convex bronchoscopy
Received 16 May 2011 ／ Accepted 11 Nov 2011
AJRS, 1(3): 197-200, 2012
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