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Abstract

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Article in Japanese

Case Report

A case of successfully treated pulmonary Mycobacterium abscessus infection associated with empyema thoracis

Takeshi Orihashia  Kazuhiro Yaterab  Masaki Matsuoa  Hiroshi Itoha  Taizo Yaguchia  Shinichi Miyazakic  Akihiro Matushitaa  Kazuhiko Machidaa  Shouichi Sugayaa  Hiroshi Mukaeb 

aDepartment of Respiratory Medicine, Wakamatsu Hospital of University of Occupational and Environmental Health, Japan
bDepartment of Respiratory Medicine, University of Occupational and Environmental Health, Japan
cChubu Rosai Hospital
dYokkaichi Municipal Hospital

ABSTRACT

A 68-year-old woman with liver cirrhosis was admitted to our hospital with high-grade fever and dyspnea on exertion in August 2007. Chest computed tomography showed right pneumothorax and consolidation with cavitation in the right upper lobe. After the chest tube insertion, yellowish purulent pleural effusion was obtained. Laboratory findings of right pleural effusion showed a high level of adenosine deaminase (101 IU/L) and a low glucose level (19.0 mg/dl) with positive smear with positive smear results of acid-fast bacilli. Mycobacterium abscessus was then confirmed by cultivation of both sputum and right pleural effusion. Her clinical symptoms and radiological findings were improved by the combination therapy with clarithromycin, amikacin, and imipenem/cilastatin for 6 months followed by combined oral treatment with clarithromycin, panipenem, and levofloxacin. To our knowledge, this is the first reported case in Japan of successfully treated empyema thoracis caused by Mycobacterium abscessus.

KEYWORDS

Nontuberuculous Mycobacteria  Empyema thoracis  Mycobacterium abscessus 

Received 7 Jun 2011 / Accepted 25 Nov 2011

AJRS, 1(3): 213-218, 2012

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