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Abstract

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Article in Japanese

Original Article

Correlations between computed tomography images and respiratory function in chronic obstructive pulmonary disease

Satoru Ishiia  Haruhito Sugiyamaa  Teruo Kirikaeb  Haruna Masakia  Go Nakaa  Motoyasu Iikuraa  Yuichiro Takedaa  Masayuki Hojoa 

aDepartment of Respiratory Medicine, National Center for Global Health and Medicine
bDepartment of Infectious Diseases, Research Institute, National Center for Global Health and Medicine

ABSTRACT

Although respiratory function tests are the primary method of assessing chronic obstructive pulmonary disease (COPD), the assessment of low-attenuation areas (LAA) on chest computed tomography (CT) has also been reported to facilitate assessment of prognosis. Our hospital installed Lung Vision® automatic analysis software, which visualizes LAA in yellow on chest CT and enables quantitative assessment. A total of seven patients met the exclusion criteria [improvement of forced expiratory volume in 1 s (FEV1) by ≥12% or ≥200 ml following inhalation of a β2 agonist (salbutamol sulfate) in four patients and test discontinuation because of metastatic lung tumor and other reasons in three patients]. Chest CT and respiratory function tests were conducted in 45 patients, and the results were assessed to determine the presence of correlations. A significant correlation (p<0.01) was observed between the Lung Vision score and FEV1/FVC, FEV1.

KEYWORDS

COPD  Low attenuation area  Low attenuation area volume 

Received 4 Sep 2013 / Accepted 19 Nov 2013

AJRS, 3(2): 221-226, 2014

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