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Abstract

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Article in Japanese

Case Report

Intractable bladder hemorrhage caused by bladder metastasis in a patient with advanced pulmonary adenocarcinoma

Akihiko Goto  Takeo Ito  Taiki Masuda  Yutaka Mukai  Mari Yamasue  Jun-ichi Kadota 

Department of Respiratory Medicine and Infectious Diseases, Oita University Faculty of Medicine

ABSTRACT

A 58-year-old man was diagnosed as pulmonary adenocarcinoma (cT4N3M0, stage IIIb). Although he underwent first-line chemotherapy, multiple metastases were found thereafter. Only a bladder metastasis enlarged after second-line chemotherapy, and he was hospitalized for control of continuous bladder hemorrhaging. Although the bladder hemorrhaging was intractable, it was controlled by transcatheter arterial embolization. He underwent partial cystectomy afterward, and the resected bladder specimens demonstrated metastases from the pulmonary adenocarcinoma. A bladder metastasis from pulmonary adenocarcinoma is very rare. As a cause of only a bladder metastasis enlargement, we considered a possibility of the pharmacokinetic drug concentration difference of each organ or the tumor cell heterogeneity about drug resistance.

KEYWORDS

Pulmonary adenocarcinoma  Bladder matastasis  Bladder hemorrhage  Transcatheter arterial embolization 

Received 19 Jul 2013 / Accepted 20 Jan 2014

AJRS, 3(3): 401-404, 2014

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