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Article in Japanese
Abstract
Topics Series Cell and molecular biology
Biomarkers in respiratory diseases, focusing on periostin
Shoichiro Ohtaa Kenji Izuharab
aDepartment of Laboratory Medicine, Saga Medical School
bDivision of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School
ABSTRACT
Periostin, a matricellular protein, is upregulated in various inflammatory and/or fibrotic diseases. We have developed outstanding periostin detection systems using enzyme-linked immunosorbent assay and demonstrated periostin as a useful biomarker. A clinical application of periostin is expected for bronchial asthma and idiopathic interstitial pneumonias among respiratory diseases.
KEYWORDS
Bronchial asthma Idiopathic interstitial pneumonia Fibrosis Companion diagnostics Stratified medicine
AJRS, 3(5): 617-624, 2014
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