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Abstract

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Article in Japanese

Case Report

A case of chronic eosinophilic pneumonia accompanied by bronchial asthma and airway mucosal lesions

Yoshiko Naito  Rumi Sato  Natsuko Koga  Munetsugu Nishimura  Tomoko Kamimura  Takeharu Koga 

Department of Respiratory Medicine, Asakura Medical Association Hospital

ABSTRACT

A 33-year-old man who had been treated for bronchial asthma was admitted to the hospital with fever and worsening of cough and dyspnea. Peripheral blood eosinophils had increased, and a chest radiograph showed diffuse ground-glass opacities. Bronchoscopy revealed multiple white patches on the reddened edematous bronchial mucosa, which were demonstrated as accumulations of eosinophils on biopsy. Bronchoalveolar lavage fluid contained an increased number of eosinophils, and lung biopsy samples documented infiltration of eosinophils in lung tissue. Based on these observations, the patient was diagnosed as having chronic eosinophilic pneumonia (CEP) accompanied by bronchial asthma and bronchial mucosal lesions. He was treated with systemic corticosteroids, resulting in an improvement of symptoms, along with radiological and bronchial mucosal findings. This case suggests that white patches composed of accumulated eosinophils can be seen in the airway mucosa of patients with allergic diseases, such as CEP. They are ameliorated by such treatments as systemic administration of corticosteroids.

KEYWORDS

Eosinophilic lung disease  Eosinophilic bronchitis  Bronchial asthma  Airway mucosal lesions  White patch 

Received 12 Apr 2014 / Accepted 20 Oct 2014

AJRS, 4(1): 81-85, 2015

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