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日本呼吸器学会英文誌 Respiratory Investigation
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Abstract

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Article in Japanese

Case Report

A case of eosinophilic pleural effusion associated with allergic bronchopulmonary aspergillosis

Keiko Tanimura  Wataru Furutani  Kouji Date  Yutaka Kubota 

Department of Respiratory Medicine, Kyoto Second Red Cross Hospital

ABSTRACT

Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity reaction to colonized Aspergillus species, that typically occurred in asthmatic patients. A 79-year-old man was admitted with low-grade fever and infiltrate and bronchiectasis of the left lung. He had no asthmatic symptoms, but showed eosinophilic pleural effusion. He was diagnosed with ABPA due to the following Rosenberg's criteria: peripheral blood eosinophilia, a high serum IgE level, positive precipitating serum antibodies to Aspergillus, immediate skin reaction to Aspergillus antigens, pulmonary infiltrate, and central bronchiectasis. This case was successively controlled by the addition of an antifungal agent to corticosteroids used as monotherapy, the eosinophilic pleural effusion was also improved. This is the third reported case of ABPA with eosinophilic pleural effusion. We discuss the association between ABPA and pleural effusion, and the efficacy of the combination of corticosteroids and antifungal therapy for ABPA.

KEYWORDS

Allergic bronchopulmonary aspergillosis (ABPA)  Pleural effusion  Eosinophilia 

Received 23 Oct 2014 / Accepted 13 Jan 2015

AJRS, 4(3): 249-252, 2015

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