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Abstract

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Article in Japanese

Original Article

Possible indication for surgical resection of lung cancer associated with combined pulmonary fibrosis and emphysema (CPFE)

Yuko Mizokamia  Aiko Masunagaa  Keisuke Kojimaa  Hiroshi Takahashia  Sho Saekia  Hidenori Ichiyasua  Kentaro Yoshimotob  Takeshi Morib  Makoto Suzukib  Hirotsugu Kohrogia 

aDepartment of Respiratory Medicine, Kumamoto University Hospital
bDepartment of Thoracic Surgery, Kumamoto University Hospital

ABSTRACT

Combined pulmonary fibrosis and emphysema (CPFE) complicates lung cancer at high incidence. However, its indication for surgical resection of lung cancer and the prognosis after surgery have not been assessed. The aim of this study was to clarify the clinical course and prognosis after the surgical resection of lung cancer complicated with CPFE. We conducted a retrospective study of 27 patients who underwent surgical resection of lung cancer complicated by CPFE in our hospital; 5 cases underwent thoracotomy, and 22 underwent video-assisted thoracic surgery. Partial resection was performed in 1 case, and a lobectomy was done in 26 cases. Two cases of acute exacerbation of interstitial pneumonia occurred following lung surgery. Many cases maintained their lung functions after surgery. We therefore recommend surgical resection of lung cancer complicated by CPFE in cases of pulmonary function reserved.

KEYWORDS

Combined pulmonary fibrosis and emphysema  Lung cancer  Lung resection  Postoperative complications  Acute exacerbation of interstitial pneumonia 

Received 20 Oct 2014 / Accepted 30 Apr 2015

AJRS, 4(5): 343-351, 2015

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