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Article in Japanese
Abstract
Case Report
Case report: Two cases of difficult-to-diagnose lymphoproliferative disease
Noriko Hidaa Kazuya Horiuchia Gen Ishiia Keita Kasaharaa Takashi Suzukia Tetsuya Mikogamib
aRespiratory Disease Center, Showa University Northern Yokohama Hospital
bDepartment of Pathology, Showa University Northern Yokohama Hospital
ABSTRACT
Only a few cases have been reported with malignant lymphoma accompanied by a lung lesion at the initial presentation, and such definitive diagnosis is often difficult because of various imaging findings. Here we report two patients who were diagnosed to be organizing pneumonia based on the results of transbronchial lung biopsy. But they poorly responded to steroid treatment and were given a definitive diagnosis of disease by the biopsy of other sites. When fever, elevated LDH, increased soluble interleukin-2 receptor levels, and diffuse ground-glass opacities on chest CT are present, histological diagnosis from various lesions should be actively performed to differentiate the lymphoproliferative disease.
KEYWORDS
Organizing pneumonia Diffuse large B-cell lymphoma Adult T-cell leukemia/lymphoma Soluble interleukin-2 receptor (sIL-2R)
Received 2 Dec 2014 ／ Accepted 23 Apr 2015
AJRS, 4(5): 365-369, 2015
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