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Abstract

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Article in Japanese

Case Report

Antiphospholipid syndrome accompanied by pulmonary infarcts diagnosed via thoracic lung biopsy

Takashi Ishiguroa  Noboru Takayanagia  Tomohiko Ikeyab  Naho Kagiyamaa  Yoshihiko Shimizuc  Yutaka Sugitaa  Hidesaku Asakurad 

aDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center
bDepartment of Thoracic Surgery, Saitama Cardiovascular and Respiratory Center
cDepartment of Pathology, Saitama Cardiovascular and Respiratory Center
dDepartment of Internal Medicine (III), Kanazawa University School of Medicine

ABSTRACT

A 29-year-old man was referred to our hospital for further evaluation of nodules in his right upper lung field. Although transbronchial lung biopsy was not diagnostic, we subsequently diagnosed pulmonary infarcts on the basis of thoracoscopic lung biopsy results. Enhanced computed tomography performed after histologic diagnosis showed no pulmonary artery-filling defects. During evaluation of underlying diseases that can cause pulmonary infarcts, positive test results for lupus anticoagulant were obtained twice, and we diagnosed antiphospholipid syndrome. Pulmonary infarcts should be considered as a differential diagnosis of solitary pulmonary nodule, and antiphospholipid antibody should be investigated in such cases.

KEYWORDS

Pulmonary infarct  Acute pulmonary thromboembolism  Lupus anticoagulant  Antiphospholipid syndrome  Thoracoscopic lung biopsy 

Received 16 Jul 2015 / Accepted 19 Sep 2015

AJRS, 5(1): 41-45, 2016

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