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日本呼吸器学会英文誌 Respiratory Investigation
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Abstract

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Article in Japanese

Case Report

Anti-EJ antibody positive polymyositis-associated interstitial pneumonia: A case report

Fumika Uenoa  Mari Yokozekia  Fukue Ishizua  Mariko Ikedaa  Takeshi Ueharab  Takashige Miyaharaa 

aDepartment of Respiratory Medicine, Nagano Matsushiro General Hospital
bDepartment of Laboratory Medicine, Shinshu University School of Medicine

ABSTRACT

A 66-year-old woman visited our hospital because of abnormal chest radiograph on a health checkup, which shows bilateral consolidation, reticular shadow, and volume loss. On physical examination, she had exertional dyspnea, pain in the left knee joint, muscle weakness of limbs, and keratinization of fingers and thumbs. She was pathologically diagnosed with myositis accompanied by interstitial pneumonia. Her serological examination revealed she has anti-EJ antibody, among anti-aminoacyl tRNA synthetase (ARS) antibodies. Her symptoms and lung lesions have improved by combination therapy of corticosteroid and immunosuppressant. We suggest that anti-ARS antibody is very useful to make a diagnosis and perhaps to predict a prognosis.

KEYWORDS

Anti-aminoacyl-tRNA synthetase antibodies  Anti-EJ antibodies  Interstitial pneumonia  Polymyositis  Dermatomyositis 

Received 17 Dec 2015 / Accepted 27 Apr 2016

AJRS, 5(5): 250-254, 2016

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