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Abstract

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Article in Japanese

Case Report

A case of EGFR mutation-positive gene lung cancer with acromegaly

Masako Omori-Arimuraa  Tomonobu Kawaguchia  Kayo Ijichib  Yutaka Nakashimac  Hitoshi Tsugud  Miiru Izumia, e 

aDepartment of Respiratory Medicine, Fukuoka Red Cross Hospital
bDepartment of Respiratory Medicine, Kyushu University
cDepartment of Pathology, Fukuoka Red Cross Hospital
dDepartment of Neurosurgery, Fukuoka Red Cross Hospital
eDepartment of Respiratory Medicine, Omuta Hospital

ABSTRACT

A 78-year-old man had an acromegalic face since 2000. He visited his primary care doctor in 2011 with complaints of back pain and numbness in his lower right extremity. Lung cancer was suggested by lumbar MRI revealing a metastatic bone tumor and a chest computed tomography scan revealing a tumor mass in his left lower lobe. A diagnosis of epithelial growth factor receptor (EGFR) mutation-positive lung adenocarcinoma (cT2bN2M1b, stage IV) and acromegaly was made at our hospital. Octreotide acetate was prescribed along with EGFR-TKIs after 2 months of initial treatment. The lung tumor size decreased up to 32% after initiating therapy, and progression-free survival lasted for 11 months after starting initial treatment.

KEYWORDS

Acromegaly  EGFR mutation-positive lung cancer 

Received 15 Jan 2016 / Accepted 16 Aug 2016

AJRS, 6(1): 8-12, 2017

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