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Article in Japanese
Abstract
Case Report
A case of lung nodule caused by Schizophyllum commune that was diminished by liposomal amphotericin B
Shoko Kawaia,b Miake Yamamotoa Miyako Kitazonoa Kengo Murataa Akihiko Wadaa Mikio Takamoria
aDepartment of Respiratory Medicine, Tokyo Metropolitan Tama Medical Center
bDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center
ABSTRACT
A 59-year-old woman with myelodysplastic syndromes was admitted to the Tokyo Metropolitan Tama Medical Center to undergo an umbilical cord blood transplant. A lung nodule was found by computed tomography 2 months after administration, and Schizophyllum commune was cultured from her sputum. Serum immunoglobulin G against S. commune was positive, and she was diagnosed as having lung nodule caused by S. commune. She was treated with liposomal amphotericin B, and the nodule diminished. Including our case, 6 cases of lung infection resulting from S. commune have been reported. Infection by S. commune should be included in the differential diagnosis of a lung nodule in immunocompromised patients. Further collection of such cases is required.
KEYWORDS
Schizophyllum commune Liposomal amphotericin B Myelodysplastic syndromes Umbilical cord blood transplant
Received 18 Aug 2016 ／ Accepted 20 Jan 2017
AJRS, 6(3): 165-169, 2017
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