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Abstract

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Article in Japanese

Case Report

A case of lymphomatoid granulomatosis with rapidly progressive respiratory failure

Yu Kusakaa  Tsukasa Okamotoa  Tomoko Sakaia  Hiroshi Takasakib  Takehiko Obab  Susumu Isogaib 

aDepartment of Respiratory Medicine, Tokyo Medical and Dental University
bDepartment of Respiratory Medicine, Ome Municipal General Hospital

ABSTRACT

A 63-year-old woman with persistent fever visited our hospital. A chest CT scan demonstrated multiple pulmonary nodules. Subsequently, we performed a CT-guided percutaneous lung biopsy. A week later the pulmonary nodules enlarged rapidly and ground-glass opacities appeared diffusely in both lung fields. The patient developed acute respiratory failure requiring mechanical ventilation. We diagnosed lymphomatoid granulomatosis grade III based on the histological findings and started chemotherapy with rituximab, which was effective temporarily. However, the tumor quickly progressed and the patient's health deteriorated; she died a month and a half after the first medical examination. Because of the extremely acute progression, we herein report the details of this case.

KEYWORDS

Lymphomatoid granulomatosis  Rituximab  Ground glass opacity 

Received 14 Jun 2016 / Accepted 26 Dec 2016

AJRS, 6(3): 205-209, 2017

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