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Abstract

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Article in Japanese

Case Report

A case of multiple system atrophy diagnosed following acute hypercapnic respiratory failure

Tomoyo Taketaa  Miho Suginakab  Koichi Furukawab  Naoki Nakamurab  Takao Kamimorib  Hiroshi Fujiwarab 

aDepartment of Respiratory Medicine, Hoshigaoka Medical Center
bDepartment of Respiratory Medicine, Yodogawa Christian Hospital

ABSTRACT

A 67-year-old woman with interstitial pneumonia underwent portable monitoring because sleep apnea syndrome was suspected due to snoring. Results showed an apnea-hypopnea index (AHI) of 40.2/hr. We administered nasal continuous positive airway pressure, but the resulting improvement in AHI was insufficient. Overnight polysomnography demonstrated hypoventilation with severe hypoxia. She subsequently complained of bilateral leg weakness and hoarseness that was suspected to be due to a neuromuscular disorder, but we could not make a definitive diagnosis. While under observation, she suddenly developed acute hypercapnic respiratory failure, and we finally diagnosed her with multiple system atrophy (MSA). We report this case here because MSA initially presenting with hypoventilation that culminates in acute hypercapnic respiratory failure is rare.

KEYWORDS

Multiple system atrophy  Acute hypercapnic respiratory failure  Polysomnography 

Received 23 Mar 2017 / Accepted 26 Jul 2017

AJRS, 6(6): 483-487, 2017

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