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Abstract

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Article in Japanese

Case Report

Two cases of invasive thymoma revealing endobronchial extension after radiation therapy

Takuma Katano  Satoshi Ikeda  Kousuke Isomoto  Akimasa Sekine  Eri Hagiwara  Takashi Ogura 

Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center

ABSTRACT

While invasive thymoma commonly invades neighboring structures in the thorax, direct polypoid tumor extension into the bronchus is extremely rare. Herein, we report two cases of invasive thymoma with endobronchial polypoid extension after radiation therapy. Both cases were classified as unresectable Masaoka stage III disease. After a few years of radiation therapy, the tumors showed gradual endobronchial polypoid growth from the peripheral bronchus toward the proximal bronchus, and biopsy revealed recurrent disease. The vulnerability of the tissue of the pleura/lung/peripheral bronchus to the effects of radiation therapy may increase the risk of polypoid tumor extension into the airway. These cases suggest the importance of periodic follow-up after radiation therapy.

KEYWORDS

Thymoma  Endobronchial extension  Radiation therapy 

Received 14 Sep 2017 / Accepted 26 Dec 2017

AJRS, 7(2): 100-104, 2018

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