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Abstract

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Article in Japanese

Case Report

A case of non-specific interstitial pneumonia and organizing pneumonia overlap pattern with anti-EJ antibody and anti-Ro-52 antibody

Kaoru Inoue  Kota Murohashi  Yu Hara  Kentaro Yumoto  Shuhei Teranishi  Takeshi Kaneko 

Department of Pulmonology, Yokohama City University Graduate School of Medicine

ABSTRACT

A 60-year-old woman visited our hospital because of dyspnea several months ago. She did not present symptoms associated with myositis; however, high-resolution computed tomography (CT) chest scan revealed interstitial pneumonia with serum anti-EJ and anti-Ro-52 antibody. Surgical lung biopsy (SLB) specimens showed a non-specific interstitial pneumonia and organizing pneumonia overlap pattern. Anti-EJ antibody- and anti-Ro-52 antibody-positive interstitial pneumonia is usually associated with myositis and rapidly progressive-interstitial lung disease and needs to be closely monitored.

KEYWORDS

Anti-aminoacyl tRNA synthetase antibody  Non-specific interstitial pneumonia (NSIP)  Organizing pneumonia (OP)  Anti-EJ antibody  Anti-Ro-52 antibody 

Received 24 May 2019 / Accepted 17 Jul 2019

AJRS, 8(6): 410-414, 2019

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