一般社団法人日本呼吸器学会 公式サイト
日本呼吸器学会英文誌 Respiratory Investigation
日本呼吸器学会誌 増刊号 学術講演会プログラム 抄録集 検索用
日本呼吸器学会誌 増刊号 学術講演会プログラム 抄録集 全文PDF

Abstract

Full Text of PDF Full Text of PDF (695k)
Article in Japanese

Case Report

A case of myeloid/natural killer cell precursor acute leukemia rapidly progressed having presented as an anterior mediastinal tumor

Koshi Takahashia  Akira Igarashib  Yasuko Aidaa  Hiroyuki Kishia  Sumito Inoueb  Masafumi Watanabeb 

aDepartment of Internal Medicine, Yamagata Prefectural Shinjo Hospital
bDepartment of Cardiology, Pulmonology, and Nephrology, Yamagata University Faculty of Medicine

ABSTRACT

This case involves a man in his fourties. An anterior mediastinal tumor was detected by a previous doctor who he had visited because of cough, and he was referred to our hospital for examination. A tracheal stent was inserted, as the trachea had narrowed because of the tumor. Although the diagnosis had not yet been confirmed, his respiratory condition was unfavorable, and chemotherapy was initiated immediately. A tumor biopsy was performed, and the result was a small round cell tumor; this did not help to confirm the diagnosis. After chemotherapy, the tumor shrank; however, tumor re-growth was observed. Because atypical cells were observed in the peripheral blood, he visited the Division of Hematology in our Department of Internal Medicine. As a result of examination, he was diagnosed with myeloid/natural killer (NK) cell precursor acute leukemia. Remission induction therapy was administered, but sepsis occurred, and the patient died. Myeloid/NK cell precursor acute leukemia is a rare disease that involves the formation of extranodal lesions in the mediastinum. It is assumed that respiratory physicians are first to examine mediastinal tumors for the possibility of myeloid/NK cell precursor acute leukemia. Myeloid/NK cell precursor acute leukemia needs to be noted as a differential diagnosis of mediastinal tumors.

KEYWORDS

Anterior mediastinal tumor  Myeloid/natural killer (NK) cell precursor acute leukemia 

Received 19 Mar 2019 / Accepted 6 Nov 2019

AJRS, 9(2): 93-98, 2020

Google Scholar