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Abstract

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Article in Japanese

Original Article

Clinical analysis of 36 cases with malignant chest tumors in adolescent and young adult patients at our institution

Ai Shiwaku  Jun Sakakibara  Mamoru Kunisaki  Megumi Furuta  Yuta Takashima  Hidenori Mizugaki  Hajime Asahina  Eiki Kikuchi  Naofumi Shinagawa  Satoshi Konno 

Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University

ABSTRACT

We conducted a retrospective analysis of 36 adolescent and young adult (AYA) patients with malignant chest tumors. Of those patients, 31 had lung cancer, 33 had performance status (PS) 0 or 1, and 35 had no comorbidities. Of 18 patients with lung adenocarcinoma, six had epidermal growth factor receptor (EGFR) mutations, and four had anaplastic lymphoma kinase (ALK) fusion genes. The median survival time of all patients and of the patients with lung cancer was 69.4 months and 32.8 months, respectively. AYA patient clinical characteristics, which are good PS, fewer comorbidities, and a prevalence of driver mutations, might contribute to a better prognosis for malignant chest tumors.

KEYWORDS

Adolescent and young adult generation  Malignant chest tumor  Patient clinical characteristic  Prognosis 

Received 25 Mar 2020 / Accepted 26 Jun 2020

AJRS, 9(5): 319-324, 2020

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