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日本呼吸器学会英文誌 Respiratory Investigation
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Abstract

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Article in Japanese

Case Report

A case of pulmonary Cryptococcus gattii infection

Eriko Kawate-Horiuchia  Takashi Ishiguroa  Misako Ohkusub  Katsuhiko Kameib  Yoshihiko Shimizuc  Noboru Takayanagia 

aDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center
bDepartment of Infectious Diseases, Medical Mycology Research Center, Chiba University
cDepartment of Pathology, Saitama Cardiovascular and Respiratory Center

ABSTRACT

A 22-year-old man who had been in Oregon for 10 months presented to our hospital in June 20XX with a solitary cavity in his left upper lung lobe. He had no symptoms, and a serum Cryptococcus antigen test was negative. Bronchoscopy findings were not diagnostic, and he underwent lung biopsy via thoracoscopy. The resected specimen yielded Cryptococcus sp. identified via genetic analysis as Cryptococcus gattii (VG IIc). Minimum inhibitory concentrations of fluconazole and itraconazole were administered at 32μg/mL and 1μg/mL, respectively, and we administered itraconazole for 6 months. He has not relapsed during the 4 years after cessation of the itraconazole.

KEYWORDS

Cryptococcus gattii  Pulmonary cryptococcosis  Cryptococcus antigen  Imported mycosis 

Received 2 Mar 2020 / Accepted 5 Jun 2020

AJRS, 9(5): 355-359, 2020

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