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Abstract

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Article in Japanese

Review

Summary of workshop on unilateral whole lung lavage for autoimmune pulmonary alveolar proteinosis

Toshio Ichiwataa,b  Kanji Uchidaa,c  Manabu Ishidaa,d  Keiichi Akasakaa,e  Toru Araia,f  Shinya Ohkouchia,g  Keisuke Tomiia,h  Etsuro Yamaguchia,i  Yoshikazu Inouea,f  Koh Nakataa,j 

aThe Pulmonary Alveolar Proteinosis Research Group granted by “Practical Research Project for Rare/Intractable Diseases” from Japan Agency for Medical Research and Development (AMED)
bMedical Examination Center, Urawa Medical Association
cDepartment of Anesthesiology, Graduate School of Medicine, The University of Tokyo
dDepartment of Respiratory Medicine, Kyorin University Hospital
eDepartment of Respiratory Medicine, Japanese Red Cross Society Saitama Hospital
fClinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center
gDepartment of Respiratory Medicine and Department of Occupational Health, Graduate School of Medicine, Tohoku University
hDepartment of Respiratory Medicine, Kobe City Medical Center General Hospital
iDivision of Respiratory Medicine and Allergology, Department of Medicine, Aichi Medical University School of Medicine
jClinical and Translational Research Center, Niigata University Medical and Dental Hospital

ABSTRACT

Unilateral whole lung lavage (WLL) under general anesthesia is the standard treatment for autoimmune pulmonary alveolar proteinosis (aPAP). In 1967, Ramirez-R reported on the massive pulmonary lavage (MPL) method, but the standard WLL method has not been established in the literature.
Currently, the Japanese Respiratory Society is preparing guidelines for aPAP, but in order to capture the contents related to WLL, a literature review was added to 114 cases of WLL that were performed on 20 cases of aPAP. We report the summary of the workshop about WLL which was attended by the Ministry of Health, Labour and Welfare and Japan Agency for Medical Research and Development (AMED) research group.

KEYWORDS

Autoimmune pulmonary alveolar proteinosis (aPAP)  Unilateral whole lung lavage (WLL)  The Ministry of Health  Labour and Welfare  Research on Measures for Intractable Diseases  Japan Agency for Medical Research and Development (AMED) Practical Research Project for Rare/Intractable Diseases 

Received 16 Jul 2020 / Accepted 6 Oct 2020

AJRS, 10(1): 2-9, 2021

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