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日本呼吸器学会英文誌 Respiratory Investigation
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Abstract

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Article in Japanese

Case Report

A case of anti-ARS antibody-positive interstitial pneumonia with eosinophilia in bronchoalveolar lavage fluid

Hideto Oshita  Tatsuki Takahashi  Misato Senoo  Kunihiko Funaishi  Yasuyuki Mitama  Ken Okusaki 

Department of Internal Medicine, Mihara Medical Association Hospital

ABSTRACT

A 66-year-old woman complained of dyspnea on exertion. Her chest CT showed ground-glass opacities on bilateral lower lobes, suggesting nonspecific interstitial pneumonia. She showed mechanic's hand and was positive for serum anti-aminoacyl tRNA synthetase (anti-ARS) antibody. Bronchoscopy revealed eosinophilia (30%) in the bronchoalveolar lavage fluid; thus, eosinophilic pneumonia needed to be ruled out. The bilateral lung shadows disappeared when prednisolone was commenced. Since anti-ARS antibody-positive interstitial pneumonia may show eosinophilia in bronchoalveolar lavage fluid, it is necessary to carefully distinguish it from eosinophilic pneumonia via image findings and physical examination.

KEYWORDS

Anti-aminoacyl tRNA synthetase (ARS) antibody  Bronchoalveolar lavage fluid (BALF)  Eosinophilic pneumonia 

Received 2 Sep 2020 / Accepted 9 Oct 2020

AJRS, 10(1): 74-77, 2021

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